In a soon to be published paper that will appear in Analytical Biochemistry, a team of scientists from the LMU and Federal Office for Radiation Protection in Germany and Bio-Rad Laboratories compared two methods of protein normalisation utilized in western blot analysis. In the first method, known as housekeeping protein (hkp) normalisation, the signal of [...]
Nature versus nurture. These words have been drilled into us ever since we attended our first biology lecture. Not everything can be predicted by our genetic makeup nor is everything an outcome of our environmental exposure. Some things are a result of the environment while other traits are embedded in our genes. And then there’s [...]
Did you know that 3-D protein structures first emerged in England in 1958? How about the fact that structural work on hemoglobin started as early as 1937? Or the fact that the earliest form of cryoelectron microscopy was discovered in Germany in 1983? Neither did I. In fact, there are tons of amazing facts about [...]
In a paper published yesterday in the journal Developmental Cell, scientists in Manuela Baccarini’s lab at the University of Vienna, describe the involvement of the Raf1 protein kinase in angiogenesis-mediated endothelial cell adhesion. During the process of angiogenesis, endothelial cells migrate as a collective group in order to form new blood vessels. While it is [...]
Due to the fact that I spent most of my graduate years trying to identify which activator proteins interact with a specific gene enhancer region, studies that discuss transcriptional regulation are more likely to catch my eye than the average scientist. That is why I was particulary intrigued by a method published in Nature Genetics [...]
