To help cancer researchers investigate key pathways involved in angiogenesis, metastasis, cell proliferation, apoptosis, inflammation, and other cancer-related processes, Bio-Rad Laboratories developed the Bio-Plex Pro cell signaling assays and the Bio-Plex Pro human cancer biomarker panels. The cell signalling assays enable highly sensitive detection of phosphoproteins and total target proteins in cell and tissue lysates, [...]
Immunoassay has been the gold standard technique for detecting protein targets in biological samples for the past 50 years. Over that time, the immunoassay has undergone several iterations including RIA and EIA, each with their own set of advantages and drawbacks. While RIA exhibited tremendous sensitivity, it was a hazardous method that has since been [...]
Bio-Plex Pro human cancer biomarker assays from Bio-Rad Laboratories are a unique blend of magnetic bead–based assays designed to meet the needs of the most discerning preclinical and clinical researchers. The multiplex format enables robust and reproducible measurement of 34 biomarkers involved in: Angiogenesis Metastasis Cell proliferation Cell adhesion/migration Apoptosis Inflammation Want to learn more? [...]
Dr Antonio Facchiano, Unit Chief, Vascular Pathology Laboratory, at The Immaculate Dermopathic Institute (IDI-IRCCS) in Rome, Italy, is developing new anti-proliferation molecules and approaches for diagnostic applications in the melanoma field. Here Facchiano discusses aspects of his research employing the Bio-Plex system to investigate endogenous mechanisms that mediate cell proliferation and angiogenesis — factors controlling [...]
